Structure guided development of potent piperazine-derived hydroxamic acid inhibitors targeting falcilysin
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منابع مشابه
Cyclic Hydroxamic Acid Inhibitors of Prostate Cancer Cell Growth: Selectively and Structure Activity relationships Cyclic Hydroxamic Acid Inhibitors of Prostate Cancer Cell Growth: Selectivity and Structure Activity relationships
BACKGROUND. Clinical symptoms of prostatitis, prostatodynia, and benign prostatic hyperplasia are relieved by the pollen extract cernilton, and the water-soluble fraction of this extract selectively inhibits growth of some prostate cancer cells. A cyclic hydroxamic acid, DIBOA, has been isolated from this extract and mimics its cell growth-inhibitory properties, but the specificity of DIBOA for...
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry Letters
سال: 2021
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2020.127683